Okay, yeah, I was thinking more along the lines of a single Methuselah in a sea of people of contemporary longevity and extrapolating an existence of someone in latter midyears (albeit in decent health all things considered), just a much, much slower rate of decline from there on out.Ego wrote: ↑Thu Apr 04, 2024 7:07 am... Assuming aging is truly solved, then many of the physical accumulation problems that cause psychological changes in the elderly will be solved. The plaques will be cleared. The bloodflow maintained indefinitely. A twenty-year-old's rejuvenatory abilities working in a ninety-year-old body. It sounds crazy until you think about the advances that have been made in our lifetimes and extrapolate that out, then consider what AI will do to the trajectory...
In the not-so-science-fictiony realm, epigenitic reprogramming sounds closest to what you're talking about. I of course am sketchy on the details, but apparently there are records of our prior epigenetic state that could theoretically be determined and used to periodically 'reset' the epigenome to say our 25-year-old state. I think the principle has been demonstrated to an extent with mice as far as reversing markers of aging.
One thing I've encountered recently while devouring podcasts related to cognitive issues of aging is that it appears plaques are neither here nor there when it comes to Alzheimer's--there are drugs that can remove plaques, but they don't seem to affect the disease or its progression and come with side effects. In addition not all Alzheimer's sufferers have plaque buildup, and plaques are observed in brains without Alzheimer's. Not surprisingly when it comes to me, I'm pursuing a school of researchers/clinicians who are approaching these cognitive diseases of aging as yet other manifestations of fundamental metabolic disorder, specifically as sort of insulin resistance of the brain essentially (and hence my inner conflict of being involved in my dad's current pro-insulin resistance nutritional regimen).