Drug resistant bacteria

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black_son_of_gray
Posts: 505
Joined: Fri Jan 02, 2015 7:39 pm

Re: Drug resistant bacteria

Post by black_son_of_gray »

black_son_of_gray wrote:
Fri Apr 06, 2018 8:08 pm
I'll just add that one element to keeping drug resistant bacteria under control is having a healthy microbiome. [...] Simply put, you probably already have nasty bugs in and on you right now... but they are held in check by the huge number of other benign bugs that are competing against them for resources.
https://www.nature.com/articles/d41586-018-04957-w
High-fibre diets might ease infections caused by a virulent and common bacterium.
Source article: https://www.nature.com/articles/s41564-018-0150-6

MAC = microbiota-accessible carbohydrates = dietary fiber
CDI = Clostridium difficile infection
Together, our data demonstrate the outgrowth of MAC-utilizing taxa and the associated end products of MAC metabolism, namely, the short-chain fatty acids acetate, propionate and butyrate, are associated with decreased C. difficile fitness despite increased C. difficile toxin expression in the gut. Our findings, when placed into the context of the known fibre deficiencies of a human Western diet, provide rationale for pursuing MAC-centric dietary strategies as an alternate line of investigation for mitigating CDI.

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jennypenny
Posts: 6858
Joined: Sun Jul 03, 2011 2:20 pm

Re: Drug resistant bacteria

Post by jennypenny »

Most C. diff infections are contracted in healthcare settings, so the best prevention is to avoid inpatient care of any kind. Of those infected, most are elderly or immunocompromised -- the average person on the forum isn't in a high-risk group even if they need a short hospital stay.

As BSoG pointed out, a healthy diet that encourages a thriving microbiome, regardless of whether the person is vegan, paleo, etc, is usually the best medicine, as is avoiding being in a high-risk group when possible. ('medicine helps those who help themselves')

classical_Liberal
Posts: 2283
Joined: Sun Mar 20, 2016 6:05 am

Re: Drug resistant bacteria

Post by classical_Liberal »

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