More on Microbiome

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Ego
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Re: More on Microbiome

Post by Ego » Mon Apr 03, 2017 8:39 am

I'm trying to come up with a reason I decided this topic needed to be in DIY Skills rather than Health. What was I thinking?! The only thing I can come up with is the fecal transplant thing, which is DIY. :lol:

Yes, please move it.

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Ego
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Re: More on Microbiome

Post by Ego » Sat Sep 02, 2017 8:13 am

Nature just put out a collection of reviews of the most recent findings on the gut-brain axis. The collection is free but the individual reviews are paywalled. Lot of interesting stuff here....

https://www.nature.com/collections/dyhbndhpzv

7Wannabe5
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Re: More on Microbiome

Post by 7Wannabe5 » Sat Sep 02, 2017 9:33 am

Cool. Bookmarked. Semi-related note, the book "Systems View of Life: A Unifying Vision" which I am STRONGLY encouraging everybody to read includes a section entitled "The Rise and Rise of Epigenetics" which might particularly interest you. The parallels between modern soil science and microbiome research are kind of fascinating. My experiment with feeding my micro-orchard a diet promoting a fungal growth such as would be found at the sunny edge of a woodlands was fantastically successful. This spring I saw at least 5 different human eye visible varieties of eukaryotic organisms thriving in a spot that would recently have been described as hard-packed urban-core. If you build it, they will come.

One of the items on my wish list is a microscope with digital camera. Maybe we can all research a good deal, and then have fun posting magnified pictures of our fecal organisms? I am not even joking. I think that would be an interesting thread. Also, might help me finally break free from my pastry addiction.

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jennypenny
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Re: More on Microbiome

Post by jennypenny » Thu Jan 04, 2018 7:09 pm

NYTimes: Exercise Alters Our Microbiome. Is That One Reason It’s So Good for Us?

"...In particular, they noted widespread increases in certain microbes that can help to produce substances called short-chain fatty acids. These fatty acids are believed to aid in reducing inflammation in the gut and the rest of the body. They also work to fight insulin resistance, a precursor to diabetes, and otherwise bolster our metabolisms.

Most of the volunteers had larger concentrations of these short-chain fatty acids in their intestines after exercise, along with the microbes that produce them.

These increases were greatest, though, among the volunteers who had begun the experiment lean compared to those who were obese, the scientists found.

And perhaps not surprisingly, almost all of the changes in people’s guts dissipated after six weeks of not exercising. By and large, their microbiomes reverted to what they had been at the study’s start."

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jennypenny
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Re: More on Microbiome

Post by jennypenny » Sun Jan 14, 2018 8:12 am

theBMJ: The role of the gut microbiome in systemic inflammatory disease

Discusses autoimmune diseases, different forms of IBD, and Includes a little info on fecal transplants.

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jennypenny
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Re: More on Microbiome

Post by jennypenny » Fri May 25, 2018 3:57 am

Gut bacteria play key role in anti-seizure effects of ketogenic diet


Maybe the ideal diet for people is based on individual microbiome conditions and needs. That would explain why some people swear by vegan diets and others swear by keto/paleo/LC diets.

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Lemur
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Re: More on Microbiome

Post by Lemur » Fri Jul 06, 2018 10:48 pm

jennypenny wrote:
Fri May 25, 2018 3:57 am
Gut bacteria play key role in anti-seizure effects of ketogenic diet


Maybe the ideal diet for people is based on individual microbiome conditions and needs. That would explain why some people swear by vegan diets and others swear by keto/paleo/LC diets.
Some people feel great on carbohydrates and some don't. A big part of it, I think, is insulin sensitivity and how people uptake glucose. Some people feel very energized on carbohydrates while some, like myself, get bloated, feel hungrier, etc. Of course, we could also argue that someone who is raised on the standard western diet...who already is heading towards metabolic syndrome...tries to suddenly switch to a vegetarian diet...of course they might feel terrible!

I feel amazing on keto but terrible on vegetarian based diets; however, I don't like going full keto though because it is so expensive. Eventually settled on a compromise where I eat beans almost daily and some meats so I keep my carbs generally pretty low (under 200, ideally 100 or less) and upped my intake of fats (olive oil) for calories.

As far as what is the "right" way to eat, I really feel intermittent fasting, whether keto or vegetarian, is something everyone should try. The amount of research and health benefits coming out is pretty convincing in my opinion. Health benefits range from mental clarity, increased metabolism, lower inflammation, improved insulin sensitivity, anti-aging - it almost sounds like a magic pill. I eat on a 16 hour fast / 8 hour eating window on standard days but when I focus in I skip breakfast + lunch and eat between 6-10pm Monday-Friday.

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Ego
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Re: More on Microbiome

Post by Ego » Thu May 09, 2019 8:39 am

Ego wrote:
Thu Dec 17, 2015 9:25 pm
Ubiome normally charges $89 for their microbiome sequencing test kit but they have a special right now, three kits for $89. $29.33 each. It expires on Friday at midnight.

http://www.ubiomeblog.com/seasons-greet ... it-for-89/

Would anyone like to share a kit?
https://www.businessinsider.com/custome ... ing-2019-5

FBI raided Ubiome for their billing practices and customer complaints. I am not surprised.

I had to call them about five times to get my results released for the first test. Finally they said there was something wrong and sent me a new test but then posted the results of the first test. I sent it back and waited forever. When they finally posted my results online for the second test they appeared to be from two different people. The results were not particularly useful.

Just now I tried to log in. They now insist that I sign a HIPAA authorization for them to use my information. I refused to sign so they refuse to allow me to access the report. Not happy.

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Ego
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Re: More on Microbiome

Post by Ego » Fri May 31, 2019 2:27 am

https://www.genengnews.com/insights/mic ... s-in-mice/


The transfer of human microbiota to mice has successfully transplanted phenotypes of obesity, depression, Parkinson’s disease, schizophrenia, and multiple sclerosis. Now, we can add autism spectrum disorder (ASD) to the list. A new study suggests that the gut microbiome and its metabolites contribute to hallmark ASD behaviors and associated neuronal activity and gene expression.

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