https://jamanetwork.com/journals/jama/f ... le/2763983
Results All 5 patients (age range, 36-65 years; 2 women) were receiving mechanical ventilation at the time of treatment and all had received antiviral agents and methylprednisolone. Following plasma transfusion, body temperature normalized within 3 days in 4 of 5 patients, the SOFA score decreased, and Pao2/Fio2 increased within 12 days (range, 172-276 before and 284-366 after). Viral loads also decreased and became negative within 12 days after the transfusion, and SARS-CoV-2–specific ELISA and neutralizing antibody titers increased following the transfusion (range, 40-60 before and 80-320 on day 7). ARDS resolved in 4 patients at 12 days after transfusion, and 3 patients were weaned from mechanical ventilation within 2 weeks of treatment. Of the 5 patients, 3 have been discharged from the hospital (length of stay: 53, 51, and 55 days), and 2 are in stable condition at 37 days after transfusion.
Five minute test (similar to strep) getting rolled out next week. Someone said 70% accuracy, which might have been for the strep version, because I didn't see that mentioned in the announcement.
https://www.marketwatch.com/story/abbot ... 2020-03-27
Another test from the German company Bosch. 2.5 hours, No lab needed (but you have to buy their unit for low five figures), each test a reasonable cost. The reddit page has a link to the original article in German.
https://www.reddit.com/r/Coronavirus/co ... oduces_95/
Data about what social restriction were used with 1918 flu pandemic and the results for different cities in the US. As expected, Philadelphia was a mess. RIP Great Grandpa and family. The original article from the National Geographic is linked within. It is free with a signup (or perhaps an cloaked browser connection).
https://twitter.com/JoyceWhiteVance/sta ... 95264?s=20
CDC mask recommendations might change, from someone who might know.
https://twitter.com/DrMattMcCarthy/stat ... 19841?s=20
A hepa filter mask from your vacuum bag (cross posted)
There is speculation the virus could make young men sterile.
https://www.scmp.com/news/china/science ... t-male-sex
https://www.medrxiv.org/content/10.1101 ... 1.full.pdf
In a paper published on the preprint research platform medRxiv.org, the researchers – from Zhongnan Hospital of Wuhan University and the Hubei Clinical Research Centre for Prenatal Diagnosis and Birth Health – said they analysed blood samples from 81 men aged 20 to 54 who tested positive for the coronavirus and were hospitalised in January.
The median age of the participants was 38 and roughly 90 per cent of them had only mild symptoms. The samples were collected in the last days of their stay in hospital.
Using the samples, the team looked at the ratio of testosterone to luteinising hormone (T/LH). A low T/LH ratio can be a sign of hypogonadism, which in men is a malfunction of the testicles that could lead to lower sex hormone production.
The average ratio for the Covid-19 patients was 0.74, about half the normal level.
More on the underreporting going on
https://www.buzzfeednews.com/article/ni ... -hospitals
I would posit another reason - if they knowingly allow a ncovid patient in to get the treatment dollars then they could be liable. (I'm looking at you, radiation oncology)Doctors and nurses working in several hospitals around the country, who spoke with BuzzFeed News on the condition of not being named out of fear of repercussions, said that the official counts of COVID-19 related deaths are not comprehensive for three main reasons: a lack of tests and protective equipment means not everyone who contracted or dies of COVID-19 is diagnosed; overwhelmed hospitals may be running behind on reporting the numbers to state and county authorities; and some hospitals reporting their totals on a daily basis say they’re not being reflected promptly in county and state reports.
Asymptomatic patients (apologies if I got this from this forum, I can't remember anymore)
https://twitter.com/fascinatorfun/statu ... 14887?s=20
https://www.wired.com/story/a-south-kor ... for-trump/
“In Daegu, we had more than 10k members of Shincheonji. When we tested those who were symptomatic, 87.5 % turned out to be positive. When we tested a sample of people who weren’t symptomatic, it was 74.4%”
An existing TB vaccine might help. Germany is rolling out study using healthcare workers. I thought I remembered reading the UK was doing a similar study but that might have been something else.
https://m.medicalxpress.com/news/2020-0 ... virus.html
In other news, my data sharing addiction is still going strong and I have 20k words to write in 7 days. Happy Sunday, everyone.