Good catch on his sponsor. Though, it's exceedingly difficult to find any researcher who doesn't have some factor biasing them, but it's a very valid point.
The criticism in the journal seems to suggest we need to confirm all this and expand it to other factors. Isn't that the issue with every health study? Isn't that why we don't just have one a hard answer?
For instance:
Do these traits predict CHD risk independently of established major metabolic risk factors such as adverse total cholesterol and LDL cholesterol, blood pressure (BP), body mass, and hyperglycemia/diabetes?
All good questions, but would seem difficult to answer in any one study. Though, there seems to be a lot of studies supporting the loss of body mass and reduction of glucose readings by increasing fat and decreasing carbs. I know that's personally the case for me, as I have been measuring my body composition and blood markers over the last 8 months (BP, resting pulse, HDL, LDL, triglycerides, glucose, etc.). My diet* changes also coincide with increased exercise, so obviously there are multiple variables at work. If I had to rate which ones impacted my health the most it would be:
#1 - Calories consumed
#2 - Exercise
#3 - Higher fat ratio diet. Though, not Atkins or Paleo level. I kind of describe it as a cross between Mediterranean and Paleo.
I am going to continue to track everything going forward. It will be interesting to see how the blood markers fare over the long-term. While, I'm not that interested in the weight loss part of it, as I'm extremely confident that will continue until I hit a lower body fat level.
Some further studies:
http://www.ncbi.nlm.nih.gov/pubmed/20089734
Replacement of saturated fat by polyunsaturated or monounsaturated fat lowers both LDL and HDL cholesterol. However, replacement with a higher carbohydrate intake, particularly refined carbohydrate, can exacerbate the atherogenic dyslipidemia associated with insulin resistance and obesity that includes increased triglycerides, small LDL particles, and reduced HDL cholesterol. In summary, although substitution of dietary polyunsaturated fat for saturated fat has been shown to lower CVD risk, there are few epidemiologic or clinical trial data to support a benefit of replacing saturated fat with carbohydrate. Furthermore, particularly given the differential effects of dietary saturated fats and carbohydrates on concentrations of larger and smaller LDL particles, respectively, dietary efforts to improve the increasing burden of CVD risk associated with atherogenic dyslipidemia should primarily emphasize the limitation of refined carbohydrate intakes and a reduction in excess adiposity.
One question from this one would be the amount and ratio of poly to saturated fat. Also, it should be mentioned that slightly higher chlosterol may not be bad if it's higher HDL and higher LDL large particle, which is what other studies have suggested saturated fat does.
As a side note, this review of studies suggests the correlation of high saturated fat to heart disease isn't strong even in the studies that suggest the correlation.
http://wholehealthsource.blogspot.com/2 ... rease.html
One of the longest-running, most comprehensive and most highly cited observational studies, the Framingham study was organized by Harvard investigators and continues to this day. When investigators analyzed the relationship between saturated fat intake, serum cholesterol and heart attack risk, they were so disappointed that they never formally published the results. We know from multiple sources that they found no significant relationship between saturated fat intake and blood cholesterol or heart attack risk***.
This one basically backs up the study in my previous post. Yes, it's funded by organizations with an interest in saturated not being demonized.
https://news.osu.edu/news/2014/11/21/st ... -in-blood/
*I wanted to break my diet down further than just the "25% carb, 40-45% fat, and 30-35% protein." That 40% in fat isn't all saturated fat by any means. Though, I did replace any non/lowfat dairy with the full fat version and I use about a tablespoon of butter every day at dinner. I usually hit around 30g of saturated fat a day. Though, the day or two a week I eat beef bumps that up to high 30s in saturated fat. So, obviously I'm not eating a ton of saturated fat in the 45% fat portion of my diet.